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RNA转染试剂R4000

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现价
¥1999 ¥1999.00
英文名
EntransterTM-R4000
品牌
engreen
货号
4000-4
规格
1.5ml
货期/天
1
研究领域
分子生物学和细胞生物学
购买数量
- +
总计¥1999
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北京英格恩生物有限公司

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产品说明

产品介绍

EntransterTM-R4000是英格恩生物(Engreen Biosystem)最新研发合成的针对siRNA、microRNA、mimic、inhibitor、mRNA和shRNA等RNA的转染试剂。EntransterTM-R4000不仅可以转染小RNA,而且针对mRNA等长链RNA优化。由于纳米技术的应用,EntransterTM-R4000能做到高达90%的转染效率和60-90%的沉默效率,对难转染细胞和原代细胞也非常适用。

应用范围

小RNA转染。包括siRNA转染,miRNA,mimic,inhibitor等。 长链的mRNA和shRNA转染,针对mRNA和长链的shRNA等RNA转染优化。 可转染动物细胞、昆虫细胞等,也可以转染原代细胞、悬浮细胞和原代细胞等传统难转染细胞。

主要特点

●纳米聚合物,转染效果优于脂质体转染试剂 高效转染;

●沉默效率高,可以达到90%以上的沉默效率 低细胞毒性;

●有血清转染,无须反复更换培养基 原代细胞、悬浮细胞和敏感细胞都能转

应用于本产品的文献

1.Cancer Letters. 2019 Feb 18. STAT3 inhibition enhances CDN-induced STING signaling and antitumor immunity.(IF: 6.491.)(Stat3抑制可增强CDN诱导的STING信号和抗肿瘤免.)

2.Leukemia & Lymphoma. 2019 Jan 15. Targeting the cross-talk between the hedgehog and NF-κB signaling pathways in multiple myeloma.(多发性骨髓瘤中Hedgehog和NF-κB信号通路之间的相互作用.)

3.Chemosphere. 2019 Feb 1. Polychlorinated diphenyl sulfides can induce ROS and genotoxicity via the AhR-CYP1A1 pathway.(IF: 4.427.)(多氯代二苯硫醚可通过AHR-CYP1A1途径诱导活性氧和基因毒性.)

4.International Journal of Molecular Medicine . 2018 March 1. MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway.(间充质干细胞成骨细胞分化研究)

5.Journal of Virology . 2018 Feb 14. Lactic acid downregulates viral microRNA to promote Epstein-Barr Virus-immortalized B lymphoblastic cell adhesion and growth.(EB病毒与B淋巴细胞细胞粘附和生长研究)

6.Molecular Medicine Reports. 2018 Feb 13. Long non‑coding RNA BC168687 small interfering RNA reduces high glucose and high free fatty acid‑induced expression of P2X7 receptors in satellite glial cells.(siRNA对高糖和高游离脂肪酸环境下卫星胶纸细胞P2X7受体表达影响研究)

7.BioFactors. 2017 Nov 29. Dihydromyricetin inhibits NLRP3 inflammasome-dependent pyroptosis by activating the Nrf2 signaling pathway in vascular endothelial cells.(二氢杨梅素抑制NLRP3炎性体依赖的细胞死亡研究)

8.Experimental Cell Research. 2017 Nov 2. Erythropoietin ameliorates early brain injury after subarachnoid haemorrhage by modulating microglia polarization via the EPOR/JAK2-STAT3 pathway.(siRNA转染小鼠胶质瘤细胞与促红细胞生成素对早期脑损伤作用研究)

9. Journal of Cellular and Molecular Medicine. 2016 Nov 25. A novel P53/POMC/Gαs/SASH1 autoregulatory feedback loop activates mutated SASH1 to cause pathologic hyperpigmentation.(SASH1引起病理性色素沉着研究)

10.Journal of Experimental & Clinical Cancer Research. 2016 Sep 17. Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells.(p21基因激活与人类癌细胞中dsRNA的机制和功能)

11.Journal of Orthopaedic Translation. 2016 May 11. Knockdown of asporin affects transforming growth factor-β1-induced matrix synthesis in human intervertebral annulus cells.(Asporin的敲降可影响人类椎间环细胞中转化生长因子-β1诱导的基质合成)

12. Immunologic Research. 2016 Apr. Upregulation of long noncoding RNA TMEVPG1 enhances T helper type 1 cell response in patients with Sjögren syndrome.(LncRNA-TMEVPG1的上调可增强Sjögren综合征患者T辅助细胞1型细胞反应)

13. Tumour Biol. 2016 Mar. MiR-30a regulates the proliferation, migration, and invasion of human osteosarcoma by targeting Runx2.(MiR-30a通过靶向作用于小家畜相关的转录因子2(Runx2)进而调节人骨肉瘤细胞的增值、迁移及侵袭)

14. Stem Cells Dev. 2016 Feb. High-Efficient Transfection of Human Embryonic Stem Cells by Single-Cell Plating and Starvation.(人类胚胎干细胞)

15.Molecular Medicine Reports. 2016 Jan 27. Downregulated microRNA-23b promotes BMP9-mediated osteogenesis in C2C12 myoblast cells by targeting Runx2.(下调的microRNA-23b通过靶向Runx2促进C2C12成肌细胞中BMP9介导的骨生成)


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